pka inhibitor — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T21674L	PKA inhibitor fragment (6-22) amide Acetate	PKA inhibitor fragment (6-22) amide Acetate(121932-06-7 Free base)	PKA
	PKA inhibitor fragment (6-22) amide Acetate is a synthetic peptide which selectively inhibits PKA activity by binding to its substrate site (IC50 < 2 nM).		PKA
T75888	PKA Inhibitor Fragment (6-22) amide TFA	PKI-(6-22)-amide TFA,PKA Inhibitor Fragment (6-22) amide TFA(121932-06-7 Free base)	PKA
	PKA Inhibitor Fragment (6-22) amide TFA (PKA Inhibitor Fragment (6-22) amide TFA) is an inhibitor of the highly potent cAMP-dependent protein kinase A (PKA) inhibitor (Ki: 2.8 nM).PKA Inhibitor Fragment (6-22) amide TFA ...		PKA
T36019	PKA Inhibitor (5-24) (trifluoroacetate salt)
	PKI PKA Inhibitor (5-24) is a synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase) (Ki= 2.3 nM) derived from the active site of the skeletal muscle inhibitor protein.1It mimics the protein substrate by bind...
T3498	CCG215022		GRK , PKA
	CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50s of 0.15±0.07 μM, 0.38±0.06 μM and 3.9±1 μM for GRK2, 5 and 1, respectively.		GRK , PKA
T4S2128	Bilobetin		PKA , PPAR
	Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.		PKA , PPAR
T6304	AT7867		Akt , PKA , S6 Kinase
	AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the AGC kinase family.		Akt , PKA , S6 Kinase
T12103	MR-L2		PDE
	MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4).		PDE
T3269	Metadoxine	pyridoxine-pyrrolidone carboxylat,Metasin,Metadoxil	5-HT Receptor , PKA
	Metadoxine (Metadoxil) is a neurotransmitter stimulant.		5-HT Receptor , PKA
T2482	AT13148		ROCK , SGK , Akt , PKA , S6 Kinase
	AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.		ROCK , SGK , Akt , PKA , S6 Kinase
T7648	HA-100		Myosin , PKA , PKC
	HA-100 is an inhibitor of protein kinase		Myosin , PKA , PKC
T14069	A-3 hydrochloride		CaMK , Casein Kinase , PKA , PKC
	A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. A-3 hydrochloride also inhibits PKC and casein kinase I with Ki values of 47 µM and 80 µM, respectiv...		CaMK , Casein Kinase , PKA , PKC
T6250	H-89 dihydrochloride	Protein kinase inhibitor H-89 dihydrochloride,H 89 2HCl,5-Isoquinolinesulfonamide	PKA , S6 Kinase , Autophagy
	H-89 dihydrochloride (5-Isoquinolinesulfonamide) is a potent inhibitor of protein kinase A (PKA; IC50: 0.14 μM, Ki: 48 nM).		PKA , S6 Kinase , Autophagy
TP1351	Kemptide		PKA
	Kemptide is a synthetic heptapeptide, acting as a substrate for cAMP-dependent protein kinase (PK).		PKA
T6680	Staurosporine	Antibiotic AM-2282,AM-2282,CGP 41251	Apoptosis , PKA , Antibacterial , Antibiotic , Src , PKC , Antifungal
	Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr, phosphorylase kinase and TAOK2. Staurosporine also induces...
T6747	8-Bromo-cAMP sodium salt	8-Br-Camp sodium salt,8-Bromo-cAMP(sodium salt),8-Bromo-cAMP	PKA
	8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt) is a long-acting derivative of cyclic AMP. It is an activator of cyclic AMP-dependent protein kinase（PKA）, but resistant to degradation by cyclic AMP phosphodiesterase.		PKA
TN1694	Gliotoxin		Apoptosis , NF-κB , Wnt/beta-catenin , COX , PKA , Antibacterial , Antifection
	Gliotoxin, a Wnt signaling pathway inhibitor, induces growth inhibition and apoptosis in multiple colorectal cancer cell lines with mutations of the Wnt signaling pathway.
T2851	Daphnetin	7,8-Dihydroxycoumarin,Daphnetol	EGFR , PKA , PKC , Parasite , Autophagy
	Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-...		EGFR , PKA , PKC , Parasite , Autophagy
T1418	Bucladesine sodium	dbcAMP,Dibutyryl-cAMP sodium salt,Dibutyryl-cAMP,DC2797,Sodium dibutyryl cAMP,Bucladesine,Bucladesine sodium salt	PKA , PDE
	Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties. Bucladesine sodium is also a cAMP-dependent protein kinase (PKA) activator and a phosphodiester (PDE) inhibitor. Bucladesine sodium has anti-in...		PKA , PDE
T1606	Fasudil	HA-1077,AT877	ROCK , Serine/threonin kinase , Calcium Channel , PKA , PKC , Autophagy
	Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
T3060	Fasudil hydrochloride	Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877	ROCK , Serine/threonin kinase , Calcium Channel , HIV Protease , PKA , PKC , Autophagy
	Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.